姚楠 女,硕士,副研究员,硕士生导师,从事肿瘤血管及血管生成拟态形成的分子机制研究;基于中药抗肿瘤有效成分对肿瘤血管、血管生成拟态抑制作用的研究。主持和参加国家级、部省级课题12项,获奖成果2项,发表学术论文30余篇。
在研课题:
1. 国家自然科学基金(项目编号 81903851):“重楼总皂苷通过miR-520d-3p靶向调控Mig-7抑制骨肉瘤血管生成拟态形成及机制研究”, 时间2020.01-2022.12,经费20万,主持。
2. 江苏省基础研究计划(自然科学基金)(项目编号BK20191084):“重楼总皂苷对骨肉瘤血管生成拟态的影响及机制研究”, 时间2019.07-2022.06,经费20万,主持。
近三年发表学术论文情况:
1. Nan Yao#, Ke Ren#, Xiaojie Gu, Sujia Wu, Xin Shi, Qing Chang, Yonggang Li, Guangxin Zhou, Qiaomei Jin, Jian Zhang, Chen Wang*, Jing Zhou*. Identification of potential crucial genes associated with vasculogenic mimicry in human osteosarcoma based on gene expression profile, Neoplasma, 2020, 67(2): 286-295.
2. Zhenlin Li#, Nan Yao#, Hexiu Liu, Jing Zhou, Cong Zhang, Songlin Li, Shihui Qian, Chunfeng Zhang, Zhonglin Yang*. Fitoterapia. 2022, 158:105126.
3. Ke Ren, Yicheng Ni, Xingjia Li, Chen Wang, Qing Chang, Yonggang Li, Zengxin Gao, Sujia Wu, Xin Shi, Jie Song, Nan Yao*, Jing Zhou*. Expression profiling of long noncoding RNAs associated with vasculogenic mimicry in osteosarcoma. Journal Cellular Biochemistry, 2019, 120(8):12473-12488.
4. Ke Ren, Jian Zhang, Xiaojie Gu, Sujia Wu, Xin Shi, Yicheng Ni, Yong Chen, Jun Lu, Zengxin Gao, Chen Wang*, Nan Yao*, Migration-inducing gene-7 independently predicts poor prognosis of human osteosarcoma and is associated with vasculogenic mimicry, Experimental cell research, 2018, 369(1):80-89
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