师资队伍

孔铭

专业代码:1008

专业名称:中药学

学术/专业型:学术硕导

职务

  • 硕导
  • 硕士研究生

—— 个人简介 ——

硕导,硕士研究生,2005年毕业于南京中医药大学中药学专业。主要从事中药质量控制和创新药物研究,结合中药分析,中药炮制,中药化学,药理学等多学科的技术手段,开展中药材规范化加工,中药饮片炮制规范制定及炮制机理研究,中药制剂质量控制研究。主持并参与国家863计划,重大新药创制等国家和省部级课题10余项,新药临床前药学研究3项,发表研究论文30余篇,获南京市科技进步三等奖1项。近年来关注于中药材(饮片)加工炮制机理、规范化及技术创新研究,研究成果收录于江苏省饮片炮制规范,“硫熏中药专属性检控技术体系究与应用”获2018年度江苏分析测试科学技术奖一等奖。

擅长: 中药质量控制和创新药物研究,结合中药分析,中药炮制,中药化学,药理学等多学科的技术手段,开展中药材规范化加工,中药饮片炮制规范制定及炮制机理研究,中药制剂质量控制研究

—— 发表文章 ——

1. Ming Kong#, Huan-Huan Liu#, Jie Wu, Ming-Qin Shen, Zhi-Gang Wang, Su-Min Duan, Yan-Bo Zhang, He Zhu*, Song-Lin Li*, Effects of sulfur-fumigation on the pharmacokinetics, metabolites and analgesic activity of Radix Paeoniae Alba, Journal of Ethnopharmacology, 2018, 212: 95-105

2. Cheng-Ying Wu#, Ming Kong#, Wei Zhang, Fang Long, Jing Zhou, Shan-Shan Zhou, Jin-Di Xu, Jun Xu*, Song-Lin Li*, Impacts of sulfur-fumigation on the chemistry of ginger, Food Chemistry, 2018, 239: 953-963

3. Ya-YunXu#,FangLong#,Ye-QingZhang,Jin-DiXu,Ming Kong*,Song-LinLi*,Chemical markers for quality control of bran-fried sulfur-fumigatedPaeoniae Radix Alba,Journal of Pharmaceutical and Biomedical Analysis 2018, 159: 305-310

4. Ming Kong#, Jun Xu#, Huan-Huan Liu, Jin-Di Xu, Xiu-Yang Li, Min Lu, Chun-Ru Wang, Hu-Biao Chen*, Song-Lin Li*, Effects of boiling duration in processing of White Paeony Root on its overall quality evaluated by ultra-high performance liquid chromatography quadrupole/time-of-flight mass spectrometry based metabolomics analysis and high performance liquid chromatography quantification. Chinese Journal of Natural Medicines 2017, 15(1): 62-70

5. 孔铭,徐亚运,李松林*, 硫熏药材检控方法评述和创新研究策略探讨,药物分析杂志, 2017, 37(10): 1739-1746

6. 徐亚运,孔铭*,李松林*,硫熏白芍配方颗粒检控指标的探讨, 中草药 2017, 48: 3728-3733

7. Shan-Shan Zhou#, Jia-Wei Hu#, Ming Kong, Jin-Di Xu, Hong Shen, Hu-Biao Chen, Ming-Qin Shen, Jun Xu*, Song-Lin Li*, Less SO2 residue may not indicate higher quality, better efficacy and weaker toxicity of sulfur-fumigated herbs: Ginseng, a pilot study, Journal of Hazardous Materials, 2019, 364: 376-387

8. Li Zhou#, Jin-Di Xu#, Shan-Shan Zhou, He Zhu, Ming Kong, Hong Shen, Ye-Ting Zou, Long-Jie Cong , Jun Xu*, Song-Lin Li*, Independent or integrative processing approach of metabolite datasets from different biospecimens potentially affects metabolic pathway recognition in metabolomics, Journal of Chromatography A 2019, 1587: 146–154

9. Xiu-Yang Li#, Jin-Di Xu#, Shan-Shan Zhou, Ming Kong, Ya-Yun Xu, Ye-Ting Zou, Ya Tang, Li Zhou, Ming-Zhe Xu, Jun Xu*, Song-Lin Li*, Time segment scanning-based quasi-MRM mode by UPLC-QTOF-MS/MS for quantitative determination of herbal medicines, a case study on Mutan Cortex, Journal of Chromatography A 2018, 1581–1582 33-42

10. Shan-Shan Zhou#, Jun Xu#, Ming Kong, Ka-Man Yip, Jin-Di Xu, Hong Shen, Zhong-Zhen Zhao, Song-Lin Li*, Hu-Biao Chen*, Synchronous characterization of carbohydrates and ginsenosides yields deeper insights into the processing chemistry of ginseng, Journal of Pharmaceutical and Biochemical Analysis, 2017, 145: 59-70

11. Li Zhou#, Jin-Di Xu#, Shan-Shan Zhou, Hong Shen, Qian Mao, Ming Kong, Ye-Ting Zou, Ya-Yun Xu, Jun Xu*, Song-Lin Li*, Chemomics-based marker compounds mining and mimetic processing for exploring chemical mechanisms in traditional processing of herbal medicines, a continuous study on Rehmanniae Radix, Journal of Chromatography A 2017, 1530: 232–240

12. Li Zhou#, Jin-Di Xu#, Shan-Shan Zhou, Qian Mao, Ming Kong, Hong Shen, Xiu-Yang Li, Su-Min Duan, Jun Xu*, Song-Lin Li*, Integrating targeted glycomics and untargeted metabolomics toinvestigate the processing chemistry of herbal medicines, a case studyon Rehmanniae Radix, Journal of Chromatography A, 2016, 1472: 74–87.

13. Xiu-Yang Li#, Fang Long#, Jin-Di Xu, Hong Shen, Ming Kong, He Zhu, Ye-Qing Zhang*, Song-Lin Li*, Paeonifiorin sulfonate as a characteristic marker for specifically inspecting Chinese patent medicine Liu-Wei-Di-Huang-Wan contained sulfur-fumigated Moutan Cortex, Journal of Pharmaceutical and Biomedical Analysis 2017, 138: 283–288

14. Xiu-Yang Li#, Jin-Di Xu#, Jun Xu, Ming Kong, Shan-Shan Zhou, Eric Brand, Hu-Biao Chen, Hong-Quan Liu*, Song-Lin Li*, UPLC-QTOF-MS based metabolomics coupled with diagnostic ion exploration strategy for rapidly evaluating sulfur-fumigation caused holistic quality variation of medicinal herbs, Mutan Cortex as an example, Analytical Methods, 2016; 8: 1034-1043

15. 李秀杨, 段素敏, 刘欢欢, 徐金娣, 孔铭, 刘红权,李松林*. 特征含硫衍生物对硫熏牡丹皮检控的意义,药学学报 2016, 51(6): 972-978

—— 学术兼职 ——